Dexilant Side Effects Lawsuit: Pursuing A Kidney Injury Claim

Dexilant Side Effects Lawsuit: Pursuing A Kidney Injury Claim 2018-03-07T09:39:24+00:00
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Approved for the treatment of GERD, the proton pump inhibitor drug Dexilant may increase the risk for debilitating kidney disorders, including end-stage renal disease.

  • 600+ PPI lawsuits filed
  • MDL in New Jersey
  • New claims under evaluation

Rosen Injury Lawyers are now investigating potential PPI lawsuits on behalf of injured Dexilant patients. Call now for a free consultation.

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Approved for the treatment of GERD, the proton pump inhibitor drug Dexilant may increase the risk for debilitating kidney disorders, including end-stage renal disease.

  • 600+ PPI lawsuits filed
  • MDL in New Jersey
  • New claims under evaluation

Rosen Injury Lawyers are now investigating potential PPI lawsuits on behalf of injured Dexilant patients. Call now for a free consultation.

24/7 Free PPI Consultations

(866) 807-4631

Injured patients deserve a strong advocate in the courtroom.

— Laurence Rosen, Esq.


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Designed for the treatment of gastroesophageal reflux disease, the prescription drug Dexilant has been associated with an increased risk of chronic kidney disease and kidney failure. Hundreds of patients have already filed suit over the risk, which they say was concealed from the public as drug manufacturers hoped to capitalize on growing profits.

Heartburn Drugs Linked To Kidney Failure

Dexilant is a proton pump inhibitor drug manufactured by Takeda Pharmaceuticals, the Japanese drug manufacturer behind Prevacid. Like Prevacid, Dexilant works to reduce the amount of gastric acid secreted by the stomach, reducing the uncomfortable symptoms associated with excessive levels of stomach acid.

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Dexilant is approved specifically to treat the symptoms of gastroesophageal reflux disease (GERD) and erosive esophagitis, in which excessive stomach acid damages the lining of the esophagus. Dexilant is intended only for short-term use, though many physicians disregard this guideline in practice. Dozens of researchers in the last decade have noted a worrying trend among doctors to overprescribe PPI drugs for inappropriate indications, Medscape reports.

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A Short-Term Treatment For GERD & Esophagitis

The drug’s active ingredient, dexlansoprazole, should only be taken for limited periods of time, with a maximum of 6 months in adult patients to heal the effects of erosive esophagitis. Recommended treatment periods are far shorter for children (Dexilant is not approved for any use in patients under the age of 12) and for the treatment of GERD-related heartburn.

Dexilant is unique among proton pump inhibitors. Unlike industry leaders Nexium and Prevacid, the Dexilant capsule actually contains two releases of medication, contained in two different types of granule. One granule releases dexlansoprazole within an hour; the other granule begins to release medication later, between four and five hours after administration.

The Risk Of Acute & Chronic Kidney Damage

Proton pump inhibitors have been linked to numerous severe medical complications, including multiple forms of kidney damage. Few of these potential risks, however, appear on the drugs’ warning labels.

Acute Interstitial Nephritis: Renal Allergic Reactions

Dexilant’s labeling, for example, clearly warns patients and medical care providers about a risk for acute interstitial nephritis. That’s a form of allergic reaction, often caused by medications, in which parts of the kidney become swollen.

Acute interstitial nephritis is an extremely-serious medical condition that requires prompt medical attention. In severe cases, the allergic reaction can impair kidney function to the point of acute failure; the kidneys suddenly lose their ability to filter waste from the blood, with occasionally fatal results. Interstitial nephritis can also lead to slower forms of kidney damage, the National Library of Medicine reports.

No Warnings For CKD, Kidney Failure, Patients Note

Researchers have known that proton pump inhibitor drugs can cause acute interstitial nephritis for years. But doctors have also believed for years that proton pump inhibitors, either through their own mechanisms of action or by causing acute interstitial nephritis, can significantly increase the risk for acute kidney injuries, a dangerous form of sudden onset kidney failure.

In 2010, doctors in the British Medical Journal called proton pump inhibitors like Dexilant “an important […] cause of acute kidney injury,” noting that, when the use of these drugs was discontinued, most patients’ kidney problems resolve quickly.

And yet you won’t find acute kidney injuries mentioned on Dexilant’s label. Nor will you find the term “chronic kidney disease,” which is used to describe cases in which kidney function deteriorates gradually over time. Despite this omission, a number of recent studies have found strong evidence that long-term PPI use can increase the risk of chronic kidney disease.

A groundbreaking study led by researchers at Johns Hopkins University, for example, discovered in 2017 that patients who take PPIs are between 20% and 50% more likely to develop chronic kidney disease. The link was strengthened by a dose-response relationship; the more PPI drugs a person took, the higher their risk became.

Takeda Faces Dozens Of PPI Lawsuits

In hundreds of personal injury lawsuits, former PPI patients accuse pharmaceutical manufacturers from Takeda Pharmaceuticals to AstraZeneca of concealing serious risks from the public.

The patients, who numbered around 700 as of February 2018, all experienced severe kidney injuries after being prescribed a proton pump inhibitor drug. Dexilant and Prevacid, Takeda’s leading PPI medication, are well-represented in the claims.

What MDL Means For Heartburn Litigation

The PPI litigation has been consolidated as a Multi-District Litigation (MDL) in the US District Court of New Jersey. In August 2017, a panel of federal judges transferred every lawsuit filed over kidney injuries in federal court to Newark, allowing the once-scattered plaintiffs to work together more efficiently in pursuing their cases.

The MDL isn’t limited to claims against Takeda Pharmaceutical; rather, it encompasses every lawsuit filed over PPI-linked kidney injuries, regardless of the drug’s manufacturer.

Who Can File A Claim?

Legal experts believe thousands of eligible PPI patients have yet to step forward and file lawsuits of their own. If you or a loved one suffered kidney injuries after being prescribed Dexilant, there is still time to pursue a claim for financial compensation.

To learn more about your legal options, contact our experienced PPI attorneys today for a free consultation. We can walk you through your rights and help explain the legal process at no charge and no obligation. Just call Rosen Injury Lawyers or complete our online contact form now to get started.

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