Prilosec & Kidney Disease Lawsuit

Prilosec & Kidney Disease Lawsuit 2018-03-22T15:34:55+00:00
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Long-term use of Prilosec may cause an increased risk for severe forms of kidney damage, including both sudden and chronic kidney disease. Were you injured?

  • Acute interstitial nephritis
  • Chronic kidney disease
  • End-stage renal disease

Patients are now filing suit, accusing the drug’s manufacturer of concealing safety information.

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We believe thousands of patients have suffered kidney disease due to Prilosec.

— Laurence Rosen, Esq.

Long-term use of Prilosec may cause an increased risk for severe forms of kidney damage, including both sudden and chronic kidney disease. Were you injured?

  • Acute interstitial nephritis
  • Chronic kidney disease
  • End-stage renal disease

Patients are now filing suit, accusing the drug’s manufacturer of concealing safety information.

24/7 Free PPI Consultations

(866) 807-4631

We believe thousands of patients have suffered kidney disease due to Prilosec.

— Laurence Rosen, Esq.


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Medical researchers believe that a range of pharmaceutical drugs, proton pump inhibitors, may increase the risk for severe kidney disorders, including chronic kidney disease. A number of recent studies have found that patients who take one of these drugs, like Prilosec or Nexium, could be more likely to develop chronic kidney disease, a renal condition that can eventually lead to kidney failure. Product liability lawsuits are now being filed over this potential risk.

Prilosec’s Success Might Come At A Cost

Prilosec is a proton pump inhibitor, which means that it blocks the release of gastric acid in the stomach. The drug’s active ingredient, omeprazole, first hit the American market in 1989, providing patients and doctors with a new approach to treating GERD, or gastroesophageal reflux disease and intestinal ulcers.

Dialysis Patient

In time, the drug came into wide use, finding acceptance as an off-label (unapproved) therapy for general indigestion and heartburn. It’s not too much to suggest that, around five years after its introduction, Prilosec had become the fall-back solution for any gastroenterologist struggling to control a patient’s intestinal symptoms.

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Then, AstraZeneca’s patent on omeprazole ran out, allowing a slew of generic manufacturers to enter the market with their own versions of the drug. Anticipating a drop in sales, AstraZeneca prepared a variation on the chemical, esomeprazole, and released it as a new patented drug, Nexium. Today, Nexium outsells Prilosec by leaps and bounds, but Prilosec is still around. In fact, an over-the-counter version of Prilosec, Prilosec OTC, was introduced to pharmacies around the country in 2003, two years after AstraZeneca’s patent on omeprazole expired.

PPI Side Effect Concerns Mount

Researchers once believed that Prilosec, along with other proton pump inhibitors, was perfectly safe. In recent years, however, scientists have found a number of reasons to worry, especially for patients who have taken proton pump inhibitors for an extended period of time or at high dosages.

Acute Interstitial Nephritis

The first red flag? A series of cases of acute interstitial nephritis, a form of rapid inflammation in the kidneys. According to the American Family Physician, interstitial nephritis is a leading cause of acute kidney failure, contributing to around 15% of relevant hospitalizations. Interstitial nephritis is usually the result of an allergic reaction, often after an unwelcome chemical has been introduced to the body. Omeprazole, researchers say, is one such chemical.

In 2001, a group in the American Journal of Gastroenterology described 17 cases of acute interstitial nephritis, all linked to Prilosec’s active ingredient, with symptoms from vomiting and nausea to fever and anorexia.

FDA Forces Action On Osteoporosis Dangers

Next came fears that proton pump inhibitor drugs could increase the risk for osteoporosis and osteoporosis-related bone fractures, a danger that appears to be real and significant.

In 2010, the US Food & Drug Administration forced every PPI manufacturer, including Prilosec’s AstraZeneca, to include a new warning on their products. Proton pump inhbitors, the FDA says, carry a “possible increased risk of fractures of the hip, wrist and spine.”

Studies: Prilosec Increases Risk Of Chronic Kidney Disease

An emerging concern involves dementia, though the link, if one exists at all, is far from clear. But further study has deepened the worries expressed by earlier research on Prilosec’s affects for kidney health.

We’ve already seen that proton pump inhibitors appear to cause acute interstitial nephritis, an allergic reaction of the kidney, in some patients. Now, some researchers believe that Prilosec and similar drugs may actually trigger a cascade of progressively-severe kidney disorders, one that can end, in severe cases, with full-on kidney failure.

As Renal & Urology News reports, a number of recent studies have found that chronic kidney disease, a gradual decline in renal function, is more common among PPI patients. So is acute kidney injury, or AKI, a sudden (sometimes temporary) episode of kidney failure. In many cases, these two conditions go hand-in-hand; the patient suffers acute kidney injury, a swift and drastic decrease in kidney function, that in turn initiates chronic kidney disease.

How Filing A Lawsuit Can Help

For hundreds, if not thousands, of patients, the ultimate result of this pathway is kidney failure, in which the organs lose their ability to filter waste and dangerous chemicals out of our bodies. The only solution is to wait in line for a kidney transplant, while sitting for two to three dialysis sessions every week.

Despite growing medical evidence, AstraZeneca still hasn’t placed a warning for chronic kidney disease or kidney failure on Prilosec’s label.

Injured Prilosec patients are now turning to the civil legal system, filing product liability lawsuits en masse against AstraZeneca. In hundreds of legal claims, patients and families accuse the Swedish-American company of disregarding current medical science in the pursuit of greater profits. Many of these people blame Prilosec for causing severe kidney disorders, to say nothing of significant pain, suffering and medical expenses.

Contact A PPI Injury Attorney Now

Can you pursue compensation? If you or a loved one developed chronic kidney disease after taking Prilosec, call our experienced personal injury attorneys to learn more about your legal options. Eligible patients may be entitled to secure significant monetary damages, including compensation for their medical bills, lost earnings potential and emotional trauma. Contact our lawyers now for a free consultation and get started today.

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